Mercodia kits are based strictly on stable, monoclonal antibodies combined with other top quality reagents. This ensures safe long-term production with minimal lot-to-lot variation. By the careful selection of reagents, Mercodia products provide accurate results by first run.
The links underneath will lead you through the principle of the ELISA technology, the advantages of monoclonal antibodies and the accuracy of Mercodia´s assays. You will learn more about the hook effect and detection limit and how to calculate your results. And last but not least how you can establish your own controls.
Diabetes Mellitus is a combination of several different diseases with various etiologies. Diabetes arises when the beta cells of the Langerhans islets in the pancreas is unable to meet insulin demands in the organism, either due to functional failure and destruction of the beta cell mass or because of insulin needs due to insulin resistance or growth that are disproportionate to insulin secretory capacity.
This condition has been known for over 3000 years and today diabetes is one of the major health challenges of the 21st century. This non-communicable disease has reached epidemic proportions in all regions of the world and the prevalence of diabetes is expected to continue to rise inexorably if nothing is done to slow this epidemic. The International Diabetes Federation has predicted that the sufferers from diabetes will exceed 350 million by 2025.
Estimation of people suffering from diabetes. Zimmer et al., 2001
The two most common forms of diabetes are Insulin Dependent Diabetes Mellitus (IDDM), also called Type 1 Diabetes, and Non Insulin Dependent Diabetes Mellitus (NIDDM), also called Type 2 Diabetes.